A Red Carpet For Iron Metabolism

Iron metabolism in erythroid cells red blood cells rbcs are formed from lineage committed progenitors during erythropoiesis a highly regulated process.

A red carpet for iron metabolism. Department of pediatric oncology hematology and immunology im neuenheimer feld 153 69120 heidelberg germany. Iron is one of the most important minerals in the human body. These impressive number. Controlling iron levels in the body is a critically important part of many aspects of human health and disease.

Iron is both necessary to the body and potentially toxic. 200 billion red blood cells rbcs are produced every day requiring more than 2 1015 iron atoms every second to maintain adequate erythropoiesis. Muckenthaler mu 1 rivella s 2 hentze mw 3 galy b 4. These numbers translate into 20 ml of blood being produced each day containing 6 g of hemoglobin and 20 mg of iron.

It is also one of the most abundant minerals on the planet. 1 molecular medicine partnership unit european molecular biology laboratory and university of heidelberg im neuenheimer feld 350 69120 heidelberg germany. Iron is also important in the production of myoglobin which. A red carpet for iron metabolism 200 billion red blood cells rbcs are produced every day requiring more than 2 10 sup 15 sup iron atoms every second to maintain adequate erythropoiesis.

Request pdf a red carpet for iron metabolism 200 billion red blood cells rbcs are produced every day requiring more than 2 10 iron atoms every second to maintain adequate. Rolling out the red carpet. 2017 muckenthaler et al. These numbers translate into 20 ml of blood being produced each day containing 6 g of hemoglobin and 20 mg of iron.

Rolling out the red carpet. Human iron metabolism is the set of chemical reactions that maintain human homeostasis of iron at the systemic and cellular level. Iron is essential for many of the body s metabolic functions but its main role is in the production of hemoglobin the protein within red blood cells that binds oxygen for delivery to the various organs 2. A red carpet for iron metabolism.

Among other themes this collection highlights a selection of seminal reviews from cell about metabolic conditions such as insulin resistance and diabetes atherosclerosis and heart disease and cholesterol biology metabolic syndrome as well as obesity and metabolic regulation of the fat tissue. Cell a red carpet for iron metabolism 200 billion red blood cells rbcs are produced every day requiring more than 2 10 15 iron atoms every second to maintain adequate erythropoiesis. These numbers translate into 20 ml of blood being produced each day containing 6 g of hemoglobin and 20 mg of iron.